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International standard 16-loci DNA test

One key of high-precision parentage testing is analyzing multiple polymorphic genes. The analysis of multiple genes largely reduces the chance of serendipitous genotype match between parents and children and greatly enhances precision of parentage analysis. For example, if we find both a child and alleged father have dark skin, we cannot be sure they have biological relationship, because there are many men having dark skin genes, they all could be biological father of the child. If we find that, in addition to their dark skin, both the child and the alleged father have similar triangular-shaped eyes, and then we have more evidences that they have biological relationship. But we are still far from certain it is the truth, because there are still plenty of men with both dark skin and triangular-shaped eyes. If, in addition to both of the clues cited above, we find both the child and the alleged father have curly brown hair, which is very rare in China, and then we are much more certain that they have biological relationship… With more genetic loci involved in our analysis, the chance of serendipitous match between alleged parents and children will become less; probability of biological relationship will become higher. When we use 15 polymorphic genes and a sex gene for parentage analysis, if all genes are compatible between the child and alleged father, we are 99.99% certain they have biological relationship; if not all of the genes are compatible, we can be 100% certain they don’t have biological relationship.

 

When choosing the genes for parentage analysis, we have also considered their compliance with international standards. There are many polymorphic DNA loci in human genome, among which we may select some for Ningren parentage analysis. But if the loci were not adopted by international communities, and then the Ningren’s results would not be able to be repeated and recognized by other countries. Therefore, we choose the 13 genes of The Combined DNA Index System (or CODIS), which is adopted by Federal Bureau of Investigation of United States and widely recognized by international communities, plus two more independent genes and sex genes. As a result, Ningren’s DNA results are not only very accurate but also readily repeated and recognized by others around the world.   

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