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Parentage probability 99.99% - 99.9999%

There are two main reasons that Ningren can offer very accurate parentage analysis:

 

1, Ningren uses large number of polymorphic genes for the analysis, which largely reduces the chance of serendipitous match and greatly increases accuracy of the analysis.

 

For example, if we use traditional ABO blood typing instead of polymorphic DNA typing, and then when biological mother has type O blood and child has type B blood, all men with type B and type AB blood cannot be excluded as potential biological fathers of the child, even though only one of them is the true biological father. Since type B blood and type AB blood constitute about 33% and 8% in Asian population, there are about 41% of adult men cannot be excluded as potential father of the child.

 

Ningren employs 15 highly polymorphic genes plus one sex gene for parentage analysis. Each of the polymorphic genes has a dozen or several dozen allelic types instead of just 3 for ABO blood. Moreover, due to being located in different chromosomes, the 15 DNA loci are independent from each other. The analysis of multiple genes greatly reduce serendipitous genotype match between potential parents and children. When parental and child’s genotypes are incompatible, we can 100% exclude their biological relationship; when they are compatible, we can be 99.99% certain of their biological relationship.

 

2. Ningren uses high-precision DNA equipment. We introduce Genetic Analyzer 3130 and 3100 of Applied Biosystems of United States to Ningren lab. The instruments can precisely measure the length of DNA fragments, with precision to a single nucleotide, the basic unit of DNA. The advanced equipment makes it possible to accurately characterize DNA fragments and in turn to unambiguously analyze parentage relationship.

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